Researchers at the EPFL Neuro X Institute have created a pioneering, minimally invasive cortical electrode array inspired by soft robotics. Measuring 4 cm in diameter when deployed, the array can be inserted through a 2 cm skull opening and positioned between the skull and brain without causing harm. The design includes six spiraled arms that enhance contact with the cerebral cortex, increasing electrode surface area. Using an eversion mechanism, the array unfolds gently over the brain tissue from a cylindrical loader. Successfully tested in mini-pigs, this innovative neurotechnology holds promise for epileptic patients. The project, led by Stéphanie Lacour, combines expertise in flexible electrode development and soft robotics, representing a remarkable interdisciplinary collaboration. The array’s unique structure allows it to fit through a small opening while covering a larger surface area after deployment, addressing the challenge of minimizing invasiveness during surgical procedures. The work exemplifies a significant advancement in creating patient-specific therapeutic solutions, and the technology will be further developed by Neurosoft Bioelectronics, an EPFL spin-off, which has recently secured funding for clinical translation. The findings were published in Science Robotics, showcasing a new avenue for soft bioelectronics in neurotechnology.
