Researchers from UC Berkeley have discovered that deep sleep, known as non-REM slow-wave sleep, may protect older adults with Alzheimer’s disease pathology from memory decline. Disrupted sleep has been linked to accelerated accumulation of beta-amyloid, a protein associated with dementia-related memory loss. However, the study indicates that higher levels of deep sleep can enhance cognitive resilience against the detrimental effects of this protein. Good sleep hygiene practices may help older adults leverage this protective function against Alzheimer’s.
In a study involving 62 healthy older adults, researchers monitored sleep patterns and measured brain beta-amyloid levels. Those with elevated beta-amyloid who also experienced more deep sleep performed better on memory tests compared to those with similar amyloid levels but poorer sleep. The findings suggest that deep sleep can mitigate the cognitive impact of Alzheimer’s pathology, acting as a cognitive reserve factor.
Matthew Walker, a senior author of the study, emphasizes that sleep is a modifiable factor to improve cognitive resilience. He highlights the importance of establishing a regular sleep schedule, postulating that better sleep hygiene could significantly benefit individuals over 65, potentially curbing memory loss linked to Alzheimer’s.
