Researchers at ETH Zurich have developed flower-shaped zinc oxide particles that offer a promising method for targeted drug delivery in medical treatments, particularly for cancer and cardiovascular diseases. These particles, measuring three micrometers, can be efficiently tracked and controlled through advanced medical imaging techniques, allowing for precise application of drugs to specific areas, such as tumors, while minimizing side effects.
The unique design of these particles, resembling tiny paper flowers or desert roses, provides a large surface area for absorbing therapeutic substances. They feature fine pores between the petals which enable high loading capacity for active ingredients. Additionally, their shape allows them to scatter sound waves, making them visible under ultrasound or optoacoustic imaging, enhancing tracking capabilities.
Initial tests showed that the particles could be guided through the bloodstream and retained in predetermined locations using focused ultrasound, demonstrating effective control over drug delivery. The research indicates future applications may include delivering medications directly to tumors or blood clots. Ongoing studies will refine this technology with hopes of advancing it for clinical use. The findings are detailed in a study published in Advanced Materials.
