Researchers at Tel Aviv University and the Israel Oceanographic and Limnological Research Institute have developed innovative methods to enhance seaweed’s bioactive compounds, significantly increasing their antioxidant and UV-filtering capacities. This sustainable cultivation technique, which integrates seaweed farming with fish aquaculture, not only boosts the production of valuable compounds but also helps purify seawater and minimizes environmental impacts. Key findings include a twofold increase in antioxidants, a threefold rise in natural sunscreens, and a tenfold enhancement in protective pigments. The study explores the cultivation of three local seaweed species—Ulva, Gracilaria, and Hypnea—exposed to various stressors, leading to the creation of “super seaweed” optimized for health applications. This research holds promise for the pharmaceutical, cosmetics, food, and nutritional supplement sectors. The methodology is environmentally friendly, addressing ecological challenges like pollution and climate change, thus promoting a sustainable future. The collaborative effort involved several international researchers, with findings published in the journal Marine Drugs. By advancing seaweed biotechnology, these innovations can enhance humanity’s reliance on nature while ensuring ecological preservation. Overall, the study highlights the potential of seaweed as a versatile natural resource that benefits both health industries and the environment.